This manuscript is composed of a number of parts. The Gospels text was written in the convent of Bet Mar Yohannan of Zagba, Northern Syria, by Rabbula in 586AD
The first 14 folios, containing the illuminations, is probably from Syria, but not necessarily from a Syriac work, in the 6th century. Syriac captions were added latter. The two were joined sometime between the end of the fourteenth century and the second half of the fifteenth. The third part is ten paper folios (fols. 15–19); written in the twelth century, they carry liturgical pericopes. There was some overpainting of miniatures or folios 13 and 14, perhaps in the 15th or 16th century in Italy. Folio 13r now has perspective.
Biblioteca Medicea Laurenziana, Firenze. Plut.01.56

References: The Rabbula Gospels. Margoneetho: Syriac Orthodox Resources
The Miniatures in the Rabbula Gospels Massimo Bernabò